Archive for Events

BMRZ Workshop 2019

11th BMRZ Symposium: 22.08.2019

The 2019 BMRZ Workshop will take place on August 22nd 2019 at the Humanwissenschaftlichen Kolleg in Bad Homburg

Registration until 14th August 2019.

We have this year two guest speaker. Prof. Dr. Jochen Balbach from the Martin-Luther University in Halle-Wittenberg and Prof. Dr. Moreno Lelli from Center of Magnetic Resonance University of Florence.

09:00-09:10               Welcome and Introduction

Session 1 (09:10-10:50) Chair: Ute Hellmich

09:10-09:35                  Jakob Gebel

Oocytes on the brink of apoptosis: phosphorylation kinetics in TAp63α

09:35-10:00                  Clara Nassrin Kriebel

Multidimensional MAS-NMR on the light-driven sodium pump KR2                                  

10:00-10:25                  Nicole Erlenbach

Quantitative characterization of the non-covalent attached Ǵ spin label

10:25-10:50                 Annika Wagner

Inhibitor-induced dimerization of an essential      oxidoreductase from Africn Trypanosomes?

10:50-11:10                  Coffee

Session 2 (11:10-12:20) Chair: Harald Schwalbe

11:10-11:35                  Jiafei Mao

Exploring protein structures via engineering longitudinal spin dynamics

11:35-12:15                  Guest Speaker

Jochen Balbach, Institut für Physik, Martin-Luther-   Universität Halle-Wittenberg

Conformational plasticity of the GPCR activating parathyroid hormone

12:30-13:45               Lunch

Session 3 (13:45-15:05) Chair: Clemens Glaubitz

13:45-14:25                Guest Speaker

Moreno Lelli, Center of Magnetic Resononce, University of Florence

Efficient Solid-state NMR Dynamic Nuclear Polarisation at High Field, Fast MAS and High Temperature

 14:25-14:50                 Alberto Collauto

Investigation of RNA duplexes inside cells using PELDOR spectroscopy

14:50-15:15                  György Pintér

Study of the folding of the cold denatured barstar by temperature jump NMR spectroscopy

15:15-15:30               Coffee

Session 4 (15:30-17:10) Chair: Andreas Schlundt

15:30-15:55                  Robbin Schnieders

Development of heteronuclear-detected NMR-experiments for characterization of NH-and NH2-groups in RNA

15:55-16:20                  Alexey Cherepanov

Molecular movies at atomic resolution – sample preparation and analysis

16:20-16:55                 Anna Lopata

Exploring the conformational space of the E2-E3-ubiquitin complex

16:55-17:05               Coffee

Session 5 (17:05-17:55) Chair: Thomas Prisner

17:05-17:30                 Jörg Heiliger

                                       Site-specific DNP in a Gd(III)-labeled protein

17:30-17:55                Heiko Keller

The traffic ATPase PilF provides a link between intracellular c-di-GMP binding and DNA transport in Thermus thermophilus                    

17:55                           Closing Remarks

18:30                          BBQ Dinner at Orangerie Kurpark

 

Organisation: Simone Kobylka (email hidden; JavaScript is required)

BMRZ Workshop 2018

10th BMRZ Symposiuim: 27.06.2018

The 2018 BMRZ Workshop will take place on June 27th 2018 at the Humanwissenschaftlichen Kolleg in Bad Homburg

Programme

09:00-09:10                 Welcome and Introduction

Session 1 (09:10-10:50) Chair: Ute Hellmich

09:10-09:35                 Jakob Maciejko

DNP-enhanced Solid-State NMR reveals conformational changes of the conserved H75 during the photo cycle of Green Proteorhodopsin

09:35-10:00                 Robin Kleebach

Precursor-based selective methyl labelling of cell-free synthesized proteins

10:00-10:25                 Katja Barth

PELDOR on TmrA/B

10:25-10:50                 Katharina Weickhmann

Structure of the SAM/SAH-binding Riboswitch

10:50-11:10                 Coffee

Session 2 (11:10-12:20) Chair: Thomas Prisner

11:10-11:35                 Andreas Schlundt

HMGU/TU München, Institut für Chemie

Higher-order organization of multiple cis regulatory RNA elements for mRNA fate

 11:35-12:20                Guest Speaker

                                    Gunnar Jeschke, ETH Zürich, Physikalische Chemie

The rigid and the flexible come together: How distance distributions change our view of proteins

12:30-13:45                 Lunch

Session 3 (13:45-15:00) Chair: Johanna Baldus

13:45-14:10                 Inga Hänelt

A synergistic approach of structural biology and EPR spectroscopy to elucidate the transport mechanism of K(+) P-type ATPase KdpFABC“

14:10-14:35                 Nusrat Qureshi

Structural characterization of the ribosomal S1 protein and its mRNA complexes

14:35-15:00                 Thilo Hetzke

EDNMR of Tetracyclin Aptamer

15:00-15:10                 Coffee

Session 4 (15:10-18:00) Chair: Björn Corzilius

15:10-15:35                 Benedikt Goretzki

Structural basis of the interaction of TRPV4 with its lipid and protein functional modulators

15:35-16:00                 Sara Keyhani

Chemo-enzymatic synthesis of position-specifically modified RNA

16:00-16:45                 First half time football match Südkorea – Germany

16:45-17:15                 Coffee

17:15-18:00                 Second half time football match Südkorea – Germany

18:00                           Closing Remarks

18:30                           BBQ Dinner at Orangerie Kurpark

Organisation: Simone Kobylka (email hidden; JavaScript is required)

BMRZ Workshop 2017

9th BMRZ Symposiuim: 26.06.2017

The 2017 BMRZ Workshop will take place on June 26th 2017 at the Humanwissenschaftlichen Kolleg in Bad Homburg.

Program:

09:30-09:40                Welcome and Introduction

Session 1 (09:40-11:20) Chair: Johanna Baldus   

09:40-10:05                Kristin Möbius

Automatic and manual solid-state NMR resonance assignment and mechanistic experiments on the integral membrane protein diacylglycerol kinase

10:05-10:30                György Pintér

                                       Rational Design of New Photo Cages                       

10:30-10:55                Orawan Jakdetchai

Probing the photointermediates of light-driven sodium-ion pump from Krokinobacter eikastus by DNP enhanced solid-state NMR

10:55-11:20                Jakob Lopez, Magic Angle

                                       LOGS: Data handling made easy

11:20-11:50                Coffee

Session 2 (11:50-13:00) Chair: Jens Wöhnert

11:50-12:15                Diane Daube

Investigation of Interleukin-1β single-loop-LBT by Dynamic Nuclear Polarization (DNP)

12:15-13:00                Guest Speaker

  Remco Sprangers, MPI for Developmental Biology, Tübingen

Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme

13:00-14:30                Lunch

Session 3 (14:30-15:55) Chair: Björn Corzilius

14:30-14:55                Florian Sochor

Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation

14:55-15:20                Alberto Collauto

Investigation of the coordination sphere of the metal co-factor at the ATPase site during nucleotide turnover using hyperfine spectroscopy

15:20-15:55                Carolin Hacker

Structural Investigations of Docking  Domains in Nonribosomal Peptide Synthetases

15:55-16:25                Coffee

Session 4 (16:25-17:50) Chair: Elke Duchardt-Ferner

16:25-16:50                Iva Pritisanac

FLYA and MAGMA in automatic assignment of methyl resonances of large protein targets

16:50-17:15                Jakob Gebel

Regulation of the activity of a TAp63α by phosphorylation

17:15-17:40                Philipp Spindler

                                       Conformational Studies of DNA at 50K and Ambient Temperatures by Means of Pulsed EPR

17:40                          Closing Remarks

18:00                          BBQ Dinner at Orangerie Kurpark

There will also be a possibility to display a limited number of posters (up to 15). This would be great opportunity to catalyze discussions during the breaks. So if you are interested to show for example a poster from a recent conference, please reserve your poster space with
Simone Kobylka (email hidden; JavaScript is required). We will allocate the space on a „first come first serve“ basis.

Organisation: Simone Kobylka (email hidden; JavaScript is required)

Felix Bloch Lecture Award for Björn Corzilius

For his achievements in the field of DNP, Björn Corzilius was awarded the 2016
Felix Bloch Prize lecture award by the Magnetic Resonance Branch of the
German Chemical Society (FGMR der GDCH).

The award lecture will be presented at the 38th Annual Magnetic Resonance
Discussion Meeting taking place in Düsseldorf from 12.-15.9.2016,

For further information see: https://idw-online.de/de/news657544

BMRZ Workshop 2016

8th BMRZ Symposium: 21.6.2016

The 2016 BMRZ workshop will take place on June 21st 2016 at the Humanwissenschaftliche Kolleg in Bad Homburg.

Besides of research short talks by members of the BMRZ research groups, we will also have a workshop session. The purpose of these workshops is to lower the access barrier to all the methods and techniques available within the BMRZ, to provide practical hints, to meet well-experienced postdocs and staff members and to network in an informal atmosphere.

 

Programme

09:30 – 09:40              Welcome and Introduction Clemens Glaubitz

09:40 – 11:20                SESSION 1  Chair: Björn Corzilius

09:40 – 10:00               Deep Chatterjee             

Real time 1D NMR: a powerful tool to investigate dynamics of complex biological systems

10:00-10:20                Michaela Mehler

Trapping photointermediates of proteorhodopsin

10:20-10:40                Aisha Laguerre

Tuning nanodiscs to isotropic bicelles: structural biology of integral membrane proteins for NMR spectroscopy

10:40-11:00                Erik Henrich 

Analysis of membrane protein interactions in lipid bilayers by native mass spectrometry

11:00-11:20                Kristin Möbius

Resonance Assignment of wild-type DGK by scalar- and dipolar-coupling based ssNMR

11:20-11:40                COFFEE

11:40-13:00                SESSION 2 Chair: Ute Hellmich

11:40-12:00                Vasy Denysenkov

Overhauser DNP for in-vivo applications at 1.5 Tesla

12:00-12:20                Monu Kaushik 

Dynamic nuclear polarization enhanced solid state NMR using Gd3+ as polarizing agent

12:20-12:40                Denise Schütz

Pulsed EPR measurements on poly-ubiquintines

12:40-13:00                Elke Duchardt-Ferner

Structure and Folding of tetramethylrhodamine binding RNA Aptamers

13:00-14:00                LUNCH

14:00-15:20                SESSION 3 Chair: Jens Wöhnert

14:00-14:20                Anna Niesteruk

Insights into the M. tuberculosis kinase (PtkA) – phosphatase (MptpA) regulatory system as seen through the lens of NMR spectroscopy

14:20-14:40               Carolin Hacker

Solution stucture of the lantibiotic immunity protein Nisl and its interactions with nisin

14:40-15:00                Sven Warhaut

NMR and Single-Molecule-FRET spectroscopy of the translational adenine riboswitch

15:00-15:20                Julia Würz

Structure-based drug design by NMR        

15:20-15:30                COFFEE

15:30-16:30                WORKSHOPS

(a)       Expression, Labeliling, Analytics  ( Frank Bernhard, Krishna Saxena, Elke Duchardt-Ferner)

(b)       MAS-NMR/ DNP/ PELDOR  (Johanna Becker-Baldus, Burkhard Endeward)

(c)       Computer-based approaches (structure calculation etc.) (Sina Kazemi, Henry Jonker) 

(d)       Fast data acquisition, hardware introduction (Frank Löhr, Christian Richter)

16:30-16:40              COFFEE

16:40-17:40              Guest Speaker Chair: Thomas Prisner

Steffen Glaser, TU Munich

Optimal control pulses in magnetic resonance

17:40    Closing Remarks Harald Schwalbe

18:00    BBQ Dinner at Orangerie Kurpark

 

Organisation: Simone Kobylka (email hidden; JavaScript is required)

G-NMR School 2016 at Frankfurt

G-NMR School: A 3+2 day workshop as part of the G-NMR Initative.

  • Time: 29.2.-4.3.2016
  • Location: Goethe Universität Frankfurt, Riedberg Campus
  • Audience: Open to all NMR PhD students or PostDocs who would like to advance their in-depth knowledge about NMR techniques.
  • Program and further details: http://schwalbe.org.chemie.uni-frankfurt.de/gnmr-school

 

Workshop on Teaching Magnetic Resonance

Teaching Magnetic Resonance: A Mini-Workshop as Part of the G-NMR Initative.

  • When: November 21st 2013, 10:30 – ca. 16:00
  • Where: Goethe Universität Frankfurt, Biozentrum (Fachbereich Biochemie, Chemie, Pharmazie), Max-von-Laue-Str. 9, 60438 Frankfurt/M., Dean's Meeting Room (Biozentrum, N101, 114, above Mensa). How to find us.
  • For whom: Open to all interesed in exchanging ideas and experiences with teaching NMR and EPR.
  • Preliminary program:

     

    • Peter Schmieder, Berlin: "Lehre als Besuch an der Uni"
    • Monika Beerbaum, Berlin: "NMR für Schüler-Student-Doktorand in 2-7-14 Tagen – Auswahl von Lehrinhalten"
    • Clemens Glaubitz, Frankfurt: "NMR in biophys. Chemie für Biochemiker (BSc, MSc); FK-NMR Modul"
    • Harald Schwalbe, Frankfurt:  "NMR in der OC für Chemiker (BSc, MSc); NMR Theorie Modul"
    • Jan Ferner, Frankfurt: "Wissensprüfung im NMR-Praktikum mittels Online-Test"
    • Nils Schloerer, Köln: "NMR in Theorie und Praxis – Erfahrungen in der Chemie"
    • Gerd Gemmecker, München: "NMR-Ausbildung für Chemiker & Biochemiker an der TU München"
    • Reinhard Meusinger, Darmstadt: "Übungsaufagebn zur NMR Spektrenauswertung"
    • Zusammenfassung und Diskussion
  • Contact: Clemens Glaubitz (email hidden; JavaScript is required)
  • Administration: Simone Kobylka (email hidden; JavaScript is required)

Visit by Minister of State – Michael Boddenberg

Minister of State for Federal Affairs, Michael Boddenberg, visited the Center for Biomolecular Magnetic Resonance (BMRZ) and the Buchmann Institute of Molecular Life Sciences (BMLS) on Riedberg campus in Frankfurt/Main on 10 June 2013 as part of the 'Research Awareness Weeks'.

Staatsminister Boddenberg zu Besuch-5Harald Schwalbe (2nd from left) and Clemens Glaubitz (on the right) explain to the Minister (3rd from left) the NMR spectrometers of the BMRZ, which is the largest research infrastructure facility for high-end nuclear and electron magnetic resonance spectroscopy in Europe. During the visit, the context to the European Research Area is explained, into which the BMRZ is embedded via an extended network of other European NMR Infrastructures. Thus, the Center serves the scientific community as one of the European Large Scale Facilities for Magnetic Resonance Spectroscopy (Bio-NMR).

March 25: BMRZ 10th Anniversary Symposium

This symposium is organized to mark the 10th anniversary of the foundation of BMRZ at the Goethe University Frankfurt am Main.

Programme

9:30 – 10:10: Opening

  • C. Glaubitz, BMRZ
  • Staatssekretär I. Jung, HMWK
  • Vizepräsident M. Schubert-Zsilavecz, Goethe Universität Frankfurt
  • H. Schwalbe, BMRZ

Short Break

10:20 – 11:20: Session A / Chair T. Prisner

  • R. G. Griffin, MIT/Boston: High frequency dynamic nuclear polarization
  • C. Luchinat, CERM Florence: Highlights of some unconventional NMR experiments at CERM

Coffee Break

11:40 – 13:10: Session B / Chair J. Wöhnert

  • C. Griesinger, MPI Göttingen: Protein recognition and neurodegeneration: an NMR spectroscopic view
  • T. Carlomagno, EMBL Heidelberg: RNA-protein and protein-protein interactions in the regulation of gene expression.
  • U. Günther, Univ Birmingham: Can NMR help to decipher cancer metabolism?

Lunch

14:00 – 15:30: Session C / Chair V. Dötsch

  • M. Sattler, TUM & Helmholtz Zentrum München: NMR studies of molecular recognition and dynamics in gene regulation
  • S. Opella, UC San Diego: Structures of membrane proteins in phospholipid bilayers under physiological conditions
  • G. Jeschke, ETH Zürich: Flexibility in membrane proteins as seen by EPR spectroscopy

Coffee Break

16:00 – 17:30: Session D / Chair P. Güntert

  • R. Boelens, Univ Utrecht: Structure and dynamics in gene regulation and DNA repair
  • B. Meier, ETH Zürich: NMR and the birth of fibril structural biology
  • H. Al-Hashimi, Univ Michigan: Breathing life into nucleic acid structure by NMR – dynamics at atomic resolution

Concluding Remarks

From 18:00: Get-together, poster display, reception

Organizers: Clemens Glaubitz, Harald Schwalbe, Thomas Prisner, Volker Dötsch, Peter Güntert, Jens Wöhnert, Björn Corzilius

Contact: email hidden; JavaScript is requiredemail hidden; JavaScript is required

Conference Management: Simone Kobylka (email hidden; JavaScript is required)

March 26: G-NMR working groups meeting

On March 26, the working groups for G-NMR will meet at the BMRZ, Building N100, Lecture Hall B2. For efficiancy, it is organised one day after the 10th Anniversary of the BMRZ.

The program is:

  • 10 am Plenary session
  • 11 am Working groups: Ideas
  • 12:30 Lunch Break
  • 1:30 pm Working groups: Elaboration phase
  • 2:30 pm Plenary session – next steps

For the partitioning into the working groups, please use this doodle-link for your assignment to one of the suggested topics.

You can register on-line via the 10 Year anniversary event [here]. If you have more questions about the practical aspects of the venue and the organisation, please ask our assistant, email hidden; JavaScript is required.