Prof. Dr. Clemens Glaubitz
Research Interest
Functional and structural aspects of membrane proteins, including
- ABC transporters
- secondary transporters
- GPCRs
- microbial rhodopsins (light driven ion pumps and channels)
- lipid regulators
Main Methods
- Solid-state NMR of reconstituted membrane proteins at high field (up to 850 MHz)
- Dynamic nuclear polarization
- Membrane protein wet lab
- reconstitution of membrane proteins
- Stabel isotop labelling of membrane proteins
- Trapping of states that occur during the activity cycle of the integral membrane proteins under study
Selected recent publications:
Please click here for a full list of publications.

Coupled ATPase-adenylate kinase activity in ABC transporters
Kaur H, Lakatos-Karoly A, Vogel R, Nöll A, Tampé R, Glaubitz C, Nat Commun. 2016 Dec 22;7:13864.

Enlightening the photoactive site of channelrhodopsin-2 by DNP-enhanced solid-state NMR spectroscopy
Becker-Baldus J, Bamann C, Saxena K, Gustmann H, Brown LJ, Brown RC, Reiter C, Bamberg E, Wachtveitl J, Schwalbe H, Glaubitz C, Proc Natl Acad Sci U S A. 2015, 112, 9896-901.

Visualizing Specific Cross-Protomer Interactions in the Homo-Oligomeric Membrane Protein Proteorhodopsin by Dynamic-Nuclear-Polarization-Enhanced Solid-State NMR
Maciejko J, Mehler M, Kaur J, Lieblein T, Morgner N, Ouari O, Tordo P, Becker-Baldus J, Glaubitz C., J Am Chem Soc. 2015, 137, 9032-43.

The Structural Basis of the Green-Blue Color Switching in Proteorhodopsin determined by NMR Spectroscopy
Mao, Jiafei; Do, Nhu-Nguyen; Scholz, Frank; Reggie, Lenica; Mehler, Michaela; Lakatos, Andrea; Ong, Yean-Sin; Ullrich, Sandra; Brown, Lynda; Brown, Richard; Becker-Baldus, Johanna; Wachtveitl, Josef; Glaubitz, Clemens, J Am Chem Soc. 2014, 136, 17578-90.

Dynamic nuclear polarization-enhanced NMR on aligned lipid bilayers at ambient temperature
Jakdetchai O, Denysenkov V, Becker-Baldus J, Dutagaci B, Prisner TF, Glaubitz C, J Am Chem Soc. 2014, 136(44):15533-6.

Detecting substrates bound to the secondary multidrug efflux pump EmrE by DNP-enhanced solid-state NMR
Ong YS, Lakatos A, Becker-Baldus J, Pos KM, Glaubitz C, J Am Chem Soc. 2013, 135, 15754-62.