Prof. Dr. Clemens Glaubitz

Managing Director of BMRZ
Institute for Biophysical Chemistry
Room N202/006
Max von Laue-Str. 9
60438 Frankfurt am Main
Tel.: +49 69 798 29927
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Research Interest

Functional and structural aspects of membrane proteins, including

  • ABC transporters
  • secondary transporters
  • GPCRs
  • microbial rhodopsins (light driven ion pumps and channels)
  • lipid regulators

Main Methods

  • Solid-state NMR of reconstituted membrane proteins at high field (up to 850 MHz)
  • Dynamic nuclear polarization
  • Membrane protein wet lab
  • reconstitution of membrane proteins
  • Stabel isotop labelling of membrane proteins
  • Trapping of states that occur during the activity cycle of the integral membrane proteins under study

Selected recent publications:

Please clic here for full list of publications.

Coupled ATPase-adenylate kinase activity in ABC transporters

Kaur H, Lakatos-Karoly A, Vogel R, Nöll A, Tampé R, Glaubitz C, Nat Commun. 2016 Dec 22;7:13864.

Enlightening the photoactive site of channelrhodopsin-2 by DNP-enhanced solid-state NMR spectroscopy

Becker-Baldus J, Bamann C, Saxena K, Gustmann H, Brown LJ, Brown RC, Reiter C, Bamberg E, Wachtveitl J, Schwalbe H, Glaubitz C, Proc Natl Acad Sci U S A. 2015, 112, 9896-901.

Visualizing Specific Cross-Protomer Interactions in the Homo-Oligomeric Membrane Protein Proteorhodopsin by Dynamic-Nuclear-Polarization-Enhanced Solid-State NMR

Maciejko J, Mehler M, Kaur J, Lieblein T, Morgner N, Ouari O, Tordo P, Becker-Baldus J, Glaubitz C., J Am Chem Soc. 2015, 137, 9032-43.

The Structural Basis of the Green-Blue Color Switching in Proteorhodopsin determined by NMR Spectroscopy

Mao, Jiafei; Do, Nhu-Nguyen; Scholz, Frank; Reggie, Lenica; Mehler, Michaela; Lakatos, Andrea; Ong, Yean-Sin; Ullrich, Sandra; Brown, Lynda; Brown, Richard; Becker-Baldus, Johanna; Wachtveitl, Josef; Glaubitz, Clemens, J Am Chem Soc. 2014, 136, 17578-90.

Dynamic nuclear polarization-enhanced NMR on aligned lipid bilayers at ambient temperature

Jakdetchai O, Denysenkov V, Becker-Baldus J, Dutagaci B, Prisner TF, Glaubitz C, J Am Chem Soc. 2014, 136(44):15533-6.

Detecting substrates bound to the secondary multidrug efflux pump EmrE by DNP-enhanced solid-state NMR

Ong YS, Lakatos A, Becker-Baldus J, Pos KM, Glaubitz C, J Am Chem Soc. 2013, 135, 15754-62.